WordReference Random House Unabridged Dictionary of American English © 2026
knockout drops′, 
  1. chloral hydrate or any similar rapidly acting drug, esp. one put in a drink secretly to make the drinker unconscious.
  • 1890–95

Collins Concise English Dictionary © HarperCollins Publishers::
knockout drops
  1. a drug secretly put into someone's drink to cause stupefaction
    See also Mickey Finn

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